Medimmune Case free essay sample

MedImmune is dedicated to helping patients live better lives through advances in science and medicine. Hundreds of thousands of patients have benefited from their products, which are designed to treat or prevent infectious diseases, cancer and inflammatory diseases (Wikipedia, 2012). Their extensive research and development efforts are focused on these same areas. MedImmune acquired FluMist when it purchased Aviron in 2002. FluMist is Aviron’s lead product for development and commercialization, it’s a live virus vaccine delivered to the patient as a nasal mist for the prevention of influenza (Wikipedia, 2012). Key Issues The board of MedImmune believed that Aviron was a good strategic fit but didn’t know what to offer. We need to see all the advantages and disadvantages to come to the conclusion. With other vaccines and cancer treatment products, MedImmune wants to get larger market shares and become the leader in vaccines discovery, development, manufacture, and marketing. From the background we can see Aviron is also a biopharmaceutical company. We will write a custom essay sample on Medimmune Case or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Its lead product, FluMist, is also a live vaccine. There is a huge overlap in their researches, which can provide MedImmune a good scale of economy and cost efficiency. For Example, Synagis, as MedImmune’s main product, is the first monoclonal antibody successfully developed to combat infectious disease, and is indicated for the prevention of serious lower respiratory tract disease caused by respiratory syncytial virus (RSV) in pediatric patients at high risk of RSV disease. Aviron’s PIV-3 is a common childhood respiratory virus (Wikipedia, 2012). By purchasing Aviron, MedImmune will achieve all complete products and undergoing clinical trials including the tax credits up to 50% attached. Risk First of all, what need to be concerned is that even though FluMist helped Aviron generate $11. 7 million in revenue for the first nine months of 2001, it reported a net loss of $89. 2 million for the same period (Sullivan, J. D. , 2004). This leaves a dangerous situation for MedImmune to value Aviron with negative earnings. The problems can be grouped into two categories: problems with estimating cash flows and problems with estimating discount rates. How long will it take to get a positive earning? What number should the discount rate be? Secondly, although the company took a long time before the introduction of the vaccine FluMist, the nasal spray flu virus has been unable to obtain FDA approval for the vaccination of young children and the elderly. FluMist also exists the problem of poor sales and difficult storage. MedImmune paid $ 1. 5 billion in 2001 after the acquisition of California Aviron in launching of FluMist. At that time, MedImmune predicted that FluMist would become a blockbuster drugs. But in fact, FluMist is quite poor performance on the market. Poor estimation on potential customers and market growth should be the main reasons for the failure. Recommendation The MedImmune Company expected that the transaction will be completed in the first quarter of 2002. The transaction will write off the companys 2002 earnings levels and reach breakeven point in 2003; then the level of its cash surplus will significantly grow (MedImmune, 2001). But from both MedImmune and Avirons’ statement of operations we can see that huge gap of negative earning will not be covered in 2003. From the news afterwards we know that according to the agreement reached by the two companies, MedImmune used 1. 75 shares of outstanding stock in exchange of one Aviron’s share, total payment of $170 billion (MedImmune, 2001). If I was MedImmune’s board member I would not approve this merger. MedImmune should not ignore the huge loss and expect too much on FluMist. When facing the negative cash flow, MedImmune could value Aviron based on asset value or earning power. In asset value part, they could look into its balance sheet and focus on cur rent asset number or total asset number, and then they need to deduct liabilities to reach the net asset.

How to Create a Persuasive Speech on Non-College Education

How to Create a Persuasive Speech on Non-College Education A persuasive speech on non-college education is one which is intended to convince your audience to do something at the end. Whether you want someone to stop littering, to change the way they think about an important issue, or to take action, persuasive speeches are the most effective way to convince your audience into taking your side. But there are many elements necessary to prepare a successful persuasive essay. You Need to Know Your Topic!  You need to learn a great deal about your topic. Whatever the topic might be it is important that you learn as much as you can before you start writing your persuasive speech on non-college education. If you are not already well-versed in the subject it is important that you do research and learn as much as you can. If your argument is one which is controversial it is best to know all sides of the issue. Regardless of what side of the argument you might support, you will be much more persuasive if you are able to address the opposing side period Spend time reading articles or books about the topic. You can visit your library and ask a librarian to lend a hand in finding the best books. Make sure that any sources you use are reliable such as academic articles or books published by reputable authors. Opinion oriented sources like a news editorial might be valuable with regard to finding out what other people think about the issue, but are not necessarily something you want to quote as a reference. Fun tip: If you are allowed to choose your topic for the persuasive speech on non-college education, dont select an obvious statement which cannot be debated. Saying that littering is bad for the environment, as an example, its far too general. Theres no one who would disagree with that. When you think about your topic select something which is debatable and has definite sources. You Need to Know Your Goal!  It is important for you to understand what you are trying to achieve when writing your speech. Do you want somebody to take action at the end of your speech such that they begin doing something you spoke of during the speech? Or do you want people to vote in favor of something pertaining to your speech? You want to craft a speech such that the goal is spelled out early for your audience so they understand what your message really is. You Need to Know Your Audience!  When you write your persuasive speech on non-college education it is important that you understand your audience. An audience who knows very little about your topic will obviously need additional background information and very simple language. An audience full of experts on the topic will find such a speech particularly mundane. Likewise, if you are speaking to an audience already supportive of your view it will be much easier to persuade them to take action and you wont have to convince them that you are correct but that they need to do something. By contrast if your audience does not agree with your sentiments, you will have to focus the majority of your efforts on persuading them to consider your point of view. We hope this guide will make the effort of doing your assignment at least a little bit easier. Don’t forget our 11 facts and 20 controversial persuasive speech topics for college students that traditionally come in package.

Econ 417 Assignment 3 Essay Example | Topics and Well Written Essays - 3250 words

Econ 417 Assignment 3 - Essay Example The technological advancements are increasing day by day and the technology is becoming more and more efficient. This not only increases the efficiency of these machines but the costs of installation have also been reduced. The writer gives examples of advancements in internet, agricultural and health sectors. Later it is explained that the growth in technology is actually extremely good for economic growth. The new technology which comes in actually makes the older one obsolete and out of date. As a result, this ends up being a drawback, as new technology ends up replacing old technology. An excellent example of the history of light is mentioned here. From the campfire discovered thousands of years ago passing through candles and bulbs, today’s fluorescent lights are 143,000 times brighter than the campfires (Easterly 175). These dramatic advancements in technology have been visible over centuries and this has increased efficiency manifold. With the presence of technology the people should also have the incentive to use it. Technology without incentive may be useless and this has been seen on multiple occasions in history. The romans had the resources and the technology but they did not progress. Similarly the Chinese were the first to have access to a variety of technologies before the Europeans could even have imagined. However, they lacked an incentive for its usage and as a result the technologies remained stagnant for a long period of time before they were taken over by others. Another feature which is important along with technology is education. It has been witnessed that the productivity of workers in developed economies may be similar but their income levels may be different. A very significant reason behind this is that the different educational levels cause different levels of usage of the technology. The important factor for technological progress and for economic growth is the incentive to use these for the betterment. For the poorer countr ies the absence of technology can be both an advantage and a disadvantage. The disadvantage can be in a sense that the absence of experience of technology can result in a reversal of effect. This is because the workers will be semi-skilled or unskilled as far as the expertise is concerned. This is because they will be inexperienced in the handling of technology. They will not be able to handle the machinery and the return over the technology will be much lower than to the skilled workers of the developed nations. The advantage will be extremely essential for the developing or under-developed countries because the installation of the technology and its implementation will be extremely cost effective. The will directly have to install the technology and it will be much easier instead of upgrading the old technology or replacing it. Chapter 10 Summary This chapter begins with the examples of the incidents in the lives of three women. These women represent the poverty stricken people fr om the poorer nations of Zambia, India and Vietnam. The three families face similar situations where the death of a working person results in the isolation of the family where they are now dependent on others for survival. They are thrown into the poverty trap by the human disasters which cannot be controlled. The poor households find themselves very vulnerable to shocks such as human disasters. Such households do not have any collateral and in situations of shock they are

Analysis The Blind Faith of the One-Eyed Matador Essay

Analysis The Blind Faith of the One-Eyed Matador - Essay Example Juan Jose is a seasoned bullfighter (torero) in Spain who comes from a family with bullfighting brothers and a retired torero in his father. The author introduces the reader to the story showing Juan Jose and the Bull in the bullfighting zone and the event known as the Feria Del Pilar that is a highly anticipated date in the bullfighting calendar. The author describes the bull by revealing its name, Marques- ashy black. This allows the reader to see how the bull is huge and indicates the power and muscle that the bull has over Jose. The author also reveals that the bull is a 5-year-old bull and weighs 1,100 pounds. Russell then goes ahead to describe Juan Jose as a father of two, 38 years of age and one of top matadors in Spain. This sets the atmosphere for the reader because it makes the reader part of the action making him/ her feel present at the event (Russell 1). Russell then describes the action that occurs between Padilla and Marques. The author’s description makes the reader feel as if Marques is a human being just like Juan Jose. For instance, the author states, â€Å"Padilla and Marques are alone in the sandy pit, but a carousel of faces swirls around them. A thousand eyes beat down on Padilla, causing sweat to bead on his neck† (Russell 1). This makes the reader feel as if Juan Jose and Marques are two fighting opponents with similar attributes (Russell 1). The author describes in detail how Marques injures Juan Jose in the bullfighting match. Preceding the injury the author sets the atmosphere to prepare the reader for the worst. For instance, just after the match begins, she says, â€Å"A glancing blow from Marques unsteadies Padilla; his feet get tangled... Padilla has the bad luck, the terrible luck, of landing on his side. And now his luck gets worse† (Russell 1). This prepares the reader for the

Secondary Traits and Social Systems Essay Example for Free

Secondary Traits and Social Systems Essay Personality can be a part of complex physiology rather than the simple, straightforward approaches taken by many personality theorists.   We are constantly creating and reviving our personalities from our social experiences and our sense of acceptance or rejection by others.   In addition to our perception and pruning of our personalities due to outside forces, we are constantly changing our states of being away from a homeostatic state to physiological states of consonance and dissonance and all points in between. Therefore, a reasonable theory of personality development is possible when taking these social and physiological aspects of our natural quests for self-actualization and harmony of personality.    In agreeing that a more comprehensive theory is possible, I must disagree then, that these simple and straightforward trait approaches adequately explain or elaborate on many facets of my personality. I do not believe that my personality has remained constant, as I have had to change and do so frequently due to approval or criticism.   I believe that in moving to self-actualization, I not only go through psycho-social stages and crises, but idiosyncratic events (such as the death of a family member, a move, or any other significant change) has served to change me, as well. No one can gauge this in a simple theory, but to put it simply, the world changes me and I change the reality of the world around me.   Events that once made me happy may make my cynical and, conversely, what I was once cynical about I am now content with.   So, it is impossible to say that I was once a person with a happy and carefree personality and am now cynical or vice versa.   This all depends on the situation.   Also, my spirituality helps me to change the way I think and behave, in essence this is an ongoing change of my personality, as well.

Confinement vs. Escape in Madame Bovary :: Madame Bovary Essays

Confinement vs. Escape in Madame Bovary      Ã‚  Ã‚  Ã‚   A theme throughout Flaubert's Madame Bovary is escape versus confinement. In the novel Emma Bovary attempts again and again to escape the ordinariness of her life by reading novels, having affairs, day dreaming, moving from town to town, and buying luxuries items. It is Emma's early education described for an entire chapter by Flaubert that awakens in Emma a struggle against what she perceives as confinement. Emma's education at the convent is perhaps the most significant development of the dichotomy in the novel between confinement and escape. The convent is Emma's earliest confinement, and it is the few solicitations from the outside world that intrigue Emma, the books smuggled in to the convent or the sound of a far away cab rolling along boulevards.      Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   The chapter mirrors the structure of the book it starts as we see a satisfied women content with her confinement and conformity at the convent.      Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   At first far from being boredom the convent, she enjoyed the company of the nuns, who, to amuse her, would take her into the chapel by way of a long corridor leading from the dining hall. She played very little during the recreation period and knew her catechism well. (Flaubert 30.)Footnote1      Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   The chapter is also filled with images of girls living with in the protective walls of the convent, the girls sing happily together, assemble to study, and pray. But as the chapter progresses images of escape start to dominate. But these are merely visual images and even these images are either religious in nature or of similarly confined people.      Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   She wished she could have lived in some old manor house, like those chatelaines in low wasted gowns who spent their days with their elbows on the stone sill of a gothic window surmounted by trefoil, chin in hand watching a white plumed rider on a black horse galloping them from far across the country. (Flaubert 32.)      Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   As the chapter progresses and Emma continues dreaming while in the convent the images she conjures up are of exotic and foreign lands. No longer are the images of precise people or event but instead they become more fuzzy and

Private and Public Culture: Redefining the Borders Essay

Although defining culture into a universal definition that fits every social or academic mold can be a daunting task (Fischer, 2007), it is safe to say that every person in this world belongs to a certain culture. Recent trends in the demographics of America show exactly the possibility of separate cultures interacting, thereby indicating that multiple cultures flourish on that part of the world (Kim, 2001). In a larger sense, each country across the globe is home to a wide variety of cultures. The people who belong to each of these cultures certainly have their own cultural affiliations and the groups of people in each society also have their own as a collective body. As a result, a person, according to Richard Rodriguez, can become someone who is a part of a crowd and someone who is distinct from it. But is there really a distinction between public culture and private culture to begin with? To say the least, the notion of a private culture presumes the existence of a culture that is isolated in nature and is different from other cultures. A private culture, therefore, is one that is exclusive and cannot be easily absorbed by a foreign entity. If there are private cultures—indeed, if there are isolated and exclusive cultures—it is difficult to understand why cultures sometimes overlap with one another, why one culture shares several basic yet significant characteristics with other cultures, or why people have the tendency to absorb other cultures when the necessity and the situation call for it? I think there are no innate differences between public and private cultures simply because the notion of culture, in my opinion, is a state of the mind. Culture is something that is conditioned during the extent of a person’s life. It is something that is taught and passed-on from one generation to the next as a mental idea that seeks to differentiate the self within the group from other groups. In reality, that state of mind is only an excuse for intolerance when there should be no reason to sow hatred or indifference on the basis of cultural distinctions. Such distinctions do not carry actual value that is worth propagating for we live in a world where the only culture that exists is the culture of humanity. That being said, there is a need for college students to search for more than what we have at home simply because the home is not a bottomless source of information. To know the world around and appreciate it in its whole us is to go beyond the limitations imposed by the social institution of family. The task of understanding the rest of humanity requires us to step out of the comfort zones provided by homes and to come face-to-face with people around us. There is the culture called humanity waiting to be explored outside the home. The foundation that our families provide is incomplete in much the same way as that which society and our peers expect of us is similarly partial. There is need to explore both areas because they are two sides of the same coin in a manner of speaking. Initially, we are armed with information provided to us by our families. To develop into more complete human beings, we need to gather more comprehensive information from other sources such as formal learning institutions and social groups. However, breaking away from our families does not mean abandoning them altogether for the sake of living a more rounded life. While it is true that we need to severe ourselves from the clutches of our families at some point in time, it does not necessarily mean that we also have to totally forget them or leave them behind never to return again. What is needed is to learn to remove the limits imposed to us by our families in our attempt to understand the society and the rest of humanity while not failing to remember our so-called â€Å"roots† and tap them whenever the need arises. References Fischer, M. M. J. (2007). Culture and Cultural Analysis as Experimental Systems. Cultural Anthropology, 22(1), 1-65. Kim, E. Y. (2001). The Yin and Yang of American Culture: A Paradox. London: Intercultural Press.